Boston ADVANCE® Conditioning Contact Lens Solution, from the eye care experts at Bausch + Lomb, is step 2 in the Boston. ADVANCE® Formula Care System. This contact solution combines disinfection with a cushioning system to soothe your eyes. and provide lens wearing comfort. The disinfection system kills germs on your lenses, and the wetting and cushioning system. enhances comfortable wear by surrounding lenses with moisture. To use, wash hands. After step 1 with Boston ADVANCE Cleaner and a saline rinse, place lenses in empty lens case and fill to. top ridges with fresh Boston ADVANCE Conditioning Solution. Soak lenses for 4+ hours or overnight before wearing. After. removing lenses from lens case, apply fresh Boston ADVANCE Conditioning Solution to wet the lenses for additional. conditioning, if desired, and insert. For full instructions, see information printed inside the product carton. For fluoro silicone acrylate and silicone acrylate rigid gas permeable contact lenses. Not for use with soft (hydrophilic) contact.