Caladry Lotion plus Calamine provides temporary relief from itching and pain related to poison ivy, oak or sumac and other skin irritations. Caladryl plus Calamine is a skin protectant and topical analgesic that stops itching and dries weeping oozing rashes. You can apply the lotion to affected areas 3 or 4 times a day. Calamine plus itch reliever. Skin protectant. Topical analgesic. This item may be eligible for FSA and HSA reimbursement. For any questions you may have regarding FSAs or HSAs, please browse our FAQ.