IMODIUM® Multi-Symptom Relief is the only over-the-counter (OTC) anti-diarrheal tablet that relieves diarrhea along with symptoms of gas, bloating, cramps, and pressure. The combination of loperamide and simethicone provides fast relief from acute diarrhea and abdominal pain caused by gas. No other brand combines these two highly effective ingredients to relieve multiple symptoms of diarrhea in adults and children 6 years of age and older.