{"product_id":"perrigo-loratadine-12-hr-tabs","title":"Leader Loratadine-D 12 Hour Relief - Antihistamine \u0026 Nasal Decongestant, 30 Extended Release Tablets","description":"\u003cp\u003eLeader Loratadine-D 12 Hour combines selective H1-receptor antagonism with sympathomimetic nasal decongestant activity through 5mg loratadine and 120mg pseudoephedrine sulfate per extended-release tablet, delivering sustained 12-hour symptom management for allergic rhinitis and rhinosinusitis. The dual-mechanism formulation addresses both histamine-mediated allergic responses and adrenergic-dependent nasal mucosal edema, providing comprehensive relief from rhinorrhea, pruritus, lacrimation, and sinus pressure across indoor and outdoor allergen exposure scenarios. The extended-release matrix ensures steady medication delivery throughout the 12-hour interval, optimizing therapeutic efficacy while minimizing peak-related adverse effects. The non-sedating loratadine component maintains cognitive and psychomotor function, facilitating daytime use without impairment. The 30-tablet supply provides 15-day treatment duration with twice-daily dosing, supporting convenient allergy season management. This combination formulation represents an evidence-based therapeutic approach for individuals requiring simultaneous antihistamine and decongestant activity without requiring multiple separate medications or frequent dosing intervals.\u003c\/p\u003e","brand":"Pasteur Pharmacy","offers":[{"title":"Default Title","offer_id":51450196885846,"sku":"345802122650","price":55.89,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0842\/6238\/8054\/files\/222869660.jpg?v=1759239276","url":"https:\/\/www.oxfordum.com\/es\/products\/perrigo-loratadine-12-hr-tabs","provider":"Oxfordum","version":"1.0","type":"link"}