Prilosec OTC 20mg Delayed-Release Tablets deliver 24-hour heartburn control with just one daily pill. Each tablet contains omeprazole, a proton pump inhibitor that blocks stomach acid production at the source—providing continuous protection day and night, unlike fast-acting antacids that only work for a few hours. This 42-count package includes three complete 14-day treatment courses, making it ideal for managing frequent heartburn long-term. The advanced delayed-release formula ensures the medication safely reaches your stomach for optimal effectiveness. Swallow one tablet whole with water each morning before eating. Do not chew, crush, or suck. Full therapeutic effects develop within 1 to 4 days. Do not use for more than 14 days unless directed by a doctor. You may repeat a 14-day course once every 4 months as needed. Prilosec OTC is the number one doctor and gastroenterologist-recommended frequent heartburn medication for over 15 years.