Biofreeze Professional 360? Spray makes applying Biofreeze much easier. Featuring a continuous flow that even works upside down to reach those hard-to-reach places like the middle back, neck and other lower extremities. Biofreeze Professional effectively alleviates pain from backaches, arthritis, sore muscles and joints, sprains, strains, and bruises. Our proprietary formula is made with U.S. Pharmacopeia-grade ingredients. This dye-free formula is free of parabens and propylene glycol.