La Roche-Posay Effaclar H Iso Biome Soothing Regenerating Cream Designed for acne-prone, oily and problematic skin that has become dry after medical treatments. The exclusive active ingredient helps regulate the microbiome of the epidermis and maintain beneficial bacteria on its surface. The formula contains niacinamide and panthenol, which instantly soothe and reduce irritation. The skin becomes less oily. Method of use Apply a thin layer to a clean face. Spread around the eyes.