Manage your heartburn with Tagamet HB 200. Tagamet is the first Rx heartburn prevention product and has been trusted for over 40 years (1). It is FDA approved as a safe alternative to Ranitidine and is the only Cimetidine over-the-counter (OTC) brand with 200 mg acid reducer. Tagamet helps relieve and prevent heartburn associated with acid indigestion and sour stomach. To prevent heartburn symptoms, take Tagamet HB 200 before your first bite or any time up to 30 minutes before eating food or drinking beverages that may cause heartburn. Tagamet HB 200 helps treat heartburn and acid indigestion caused by eating or drinking certain foods and beverages, such as hot and spicy foods. To relieve heartburn symptoms associated with acid indigestion and sour stomach, take Tagamet at the first signs of discomfort, whether during or after a meal. (1) Based on Tagamet consumer purchase since 1977.