Nyquil Cold is a trusted over-the-counter medication designed to relieve symptoms associated with colds and flu. It helps to reduce fever, alleviate cough, soothe sore throats, and relieve nasal congestion, making it easier to rest. The formulation works overnight, providing relief so you can wake up feeling better. It's a convenient solution for those who are dealing with the discomfort of cold symptoms. Product Benefits. Provides Effective Relief From Nighttime Cold And Flu Symptoms. Helps Reduce Fever And Relieve Pain. Contains.